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Index > Protein center > Fstl3(Gene name) > Mouse
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  • Fstl3 (Gene name),
  • Follistatin-related protein 3 (Protein name ),  FSTL3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Fstl3(Flrg);
    Protein name:
    Follistatin-related protein 3;
    Alternative:
    Follistatin-related gene protein;Follistatin-like protein 3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with INHBA and INHBB. Interacts with FN1. Interacts with ADAM12. Interacts with MLLT10; the interaction enhances MLLT10 in vitro transcriptional activity and self-association. Interacts with MSTN.
    Function:
    The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. The nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
    Subcellular Location:
    Secreted Nucleus
    Protein Attributes:
    Sequence length:
    256
    Sequence:
    50:
    MRSGALWPLL | WGALVWTVGS | VGAVMGSEDS | VPGGVCWLQQ | GREATCSLVL | 
    100:
    KTRVSREECC | ASGNINTAWS | NFTHPGNKIS | LLGFLGLVHC | LPCKDSCDGV | 
    150:
    ECGPGKACRM | LGGRPHCECV | PNCEGLPAGF | QVCGSDGATY | RDECELRTAR | 
    200:
    CRGHPDLRVM | YRGRCQKSCA | QVVCPRPQSC | LVDQTGSAHC | VVCRAAPCPV | 
    250:
    PSNPGQELCG | NNNVTYISSC | HLRQATCFLG | RSIGVRHPGI | CTGGPKVPAE | 
    256:
    EEENFV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    KEGG:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Follistatin-related protein 3
    Cat.:
    E0127b
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Follistatin-related protein 3
    Cat.:
    E0127m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Follistatin-related protein 3
    Cat.:
    E0127r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Follistatin-related protein 3
    Cat.:
    E0127h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Follistatin-related protein 3
    Cat.:
    U0127h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Follistatin-related protein 3
    Cat.:
    U0127m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Follistatin-related protein 3
    Cat.:
    U0127b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Follistatin-related protein 3
    Cat.:
    U0127r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Follistatin-related protein 3
    Cat.:
    P0127Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Follistatin-related protein 3
    Cat.:
    P0127Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Follistatin-related protein 3
    Polyclonal Antibody for Mouse Follistatin-related protein 3
    Cat.:
    P0127Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Follistatin-related protein 3
    Monoclonal Antibody for Mouse Follistatin-related protein 3
    Monoclonal Antibody for Mouse Follistatin-related protein 3
    Monoclonal Antibody for Mouse Follistatin-related protein 3
    Protein for Mouse Follistatin-related protein 3
    Protein for Mouse Follistatin-related protein 3
    Protein for Mouse Follistatin-related protein 3
    Protein for Mouse Follistatin-related protein 3

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    Precision
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    Linearity
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    References
    1. 1.
      "Identification and characterization of a novel follistatin-like protein as a binding protein for the TGF-beta family."
      Tsuchida K. , Arai K.Y. , Kuramoto Y. , Yamakawa N. , Hasegawa Y. , Sugino H.
      J. Biol. Chem.275:40788-40796(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH INHBA
      strain: C57BL/6.
    2. 2.
      "Mouse follistatin-related protein FLRG (mouse PCTF35, PC12 cell derived trophic factor 35)."
      Uchiyama Y. , Ohsawa Y. , Kametaka S.
      Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Human follistatin-related protein: a structural homologue of follistatin with nuclear localization."
      Tortoriello D.V. , Sidis Y. , Holtzman D.A. , Holmes W.E. , Schneyer A.L.
      Endocrinology142:3426-3434(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    5. 5.
      "Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development."
      Takehara-Kasamatsu Y. , Tsuchida K. , Nakatani M. , Murakami T. , Kurisaki A. , Hashimoto O. , Ohuchi H. , Kurose H. , Mori K. , Kagami S. , Noji S. , Sugino H.
      J. Med. Invest.54:276-288(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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